|
Symbol Name ID |
Ldb3
LIM domain binding 3 MGI:1344412 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Left ventricular hypertrophy |
Endocardial fibrosis |
Left ventricular noncompaction |
Cardiomyopathy |
Dilated cardiomyopathy |
Increased left ventricular end-diastolic volume |
Sudden cardiac death |
Ventricular arrhythmia |
Left bundle branch block |
Congestive heart failure |
| Disease(s) Associated with LDB3 | ||||||||||
| dilated cardiomyopathy 1C | ||||||||||
| myofibrillar myopathy 4 |
| Mouse Phenotypes | cardiovascular system phenotype |
heart vascular congestion |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
abnormal heart morphology |
thin interventricular septum |
increased heart weight |
enlarged heart |
cardiac hypertrophy |
abnormal heart ventricle morphology |
abnormal heart left ventricle morphology |
increased heart left ventricle weight |
increased heart left ventricle size |
decreased heart left ventricle posterior wall thickness |
dilated heart left ventricle |
abnormal heart right ventricle morphology |
increased heart right ventricle size |
thin ventricular wall |
dilated heart right ventricle |
cardiac fibrosis |
dilated cardiomyopathy |
abnormal cardiovascular system physiology |
decreased cardiac muscle contractility |
atrioventricular block |
prolonged QRS complex duration |
increased response of heart to induced stress |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Ldb3tm1Chen/Ldb3tm1Chen | |||||||||||||||||||||||||||
| Ldb3tm2Chen/Ldb3tm2Chen | |||||||||||||||||||||||||||
| Ldb3tm3Chen/Ldb3tm3Chen | |||||||||||||||||||||||||||
| Ldb3tm5.2Chen/Ldb3tm5.2Chen | * | ||||||||||||||||||||||||||
| Ldb3tm6.2Chen/Ldb3tm6.2Chen | |||||||||||||||||||||||||||
| Ldb3tm2b(EUCOMM)Hmgu/Ldb3+ | |||||||||||||||||||||||||||
| Ldb3tm4Chen/Ldb3tm4Chen Myl2tm1(cre)Krc/Myl2+ (conditional) |
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| Ldb3tm4Chen/Ldb3tm4Chen A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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